ROLE OF EARLY NEONATAL HEAT ACCLIMATION IN ALLEVIATE HYPERTHERMIA-INDUCED OXIDATIVE STRESS IN RABBITS

Document Type : Original Article

Authors

1 Department of Rabbit Breeding Research, Animal Prod. Res. Inst., Agric. Res. Center, Ministry of Agric., Dokki, Giza, Egypt

2 Poultry Production Department, Faculty of Agriculture, Ain Shams University, Cairo, Egypt.

Abstract

The objective of this study was to determine role of early thermal conditioning in reducing adverse effects of heat stress during summer season. Sixty New Zealand White (NZW) kits were divided into three groups (20 kits/group). The first group was kept under normal ambient temperature (25±3°C) as control group. The second and third groups were exposed to high ambient temperature (36±3°C) at day 3 and 10 post-partum for 1h for 3 consecutive days by using electric heaters, respectively. All kits were weaned at 28 days of age.
The heat shock protein 70 (HSP70), acetylcholinesterase enzyme activity, body temperature, serum transaminases enzymes, glucose, lactate dehydrogenase enzyme, total protein, albumin, reduced glutathione, thiobarbituric acid-reactive substances, superoxide dismutase and catalase were assessed. Also, total lipid, cholesterol, triglyceride, high density lipoprotein and low density lipoprotein were assayed. Summer season was found to elicit significant deterioration in all the tested parameters confirming its impact, and season caused significant decrease in the activity of serum and brain cholinesterase but the rate of Hsp70 expression was less compared to the heat acclimated groups.
Conclusively, kit rabbits subjected to thermal conditioning at early age have the ability to cope with heat stress during the summer, which indicates the protective role of early age thermal conditioning.
 
 
 

Keywords

Files

Share

How to cite

Statistics